| 1899 | Sha'ar Zion Hospital opens in Jaffa, and closes approximately a year later due to disputes regarding the observance of Jewish dietary laws
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| 1914 | Laying of the cornerstone of Hadassah Hospital in Nahalat Binyamin, Tel Aviv |
1918
| Opening of Hadassah Hospital in Nahalat Binyamin |
| 1921 | Hadassah Hospital treats people wounded in the riots of 1920–1921 |
| 1925 | Laying of the cornerstone for Hadassah Balfour Hospital on Balfour Street |
| 1926 | Opening of Hadassah Balfour Hospital, which is run by theש Hadassah Medical Organization |
| 1931 | Hadassah Balfour Hospital is transferred to the authority and management of the Tel Aviv-Jaffa Municipality |
| 1933 | Haim Arlosoroff is assassinated. His body is taken to Hadassah Balfour Hospital |
| 1940 | When Italian aircraft bomb Tel Aviv, the wounded are taken to Hadassah Balfour Hospital |
| 1948–1949 | The War of Independence Hadassah Balfour Hospital treats people wounded in the war |
| 1949 | Internal Medicine Department C begins operations in the German school in the Sarona colony, becoming the first medical department to function in the location that will later become Yosef Serlin ("Hakirya") Maternity Hospital |
| 1951 | Yosef Serlin ("Hakirya") Maternity Hospital opens |
| 1953 | Construction of Ichilov Hospital continues after having been interrupted due to funding problems |
| 1961 | Ichilov Hospital opens in Tel Aviv |
| 1967 | The municipal Hadassah hospitals are transferred to the joint authority of the municipality and the government |
| 1967 | Dedication of the Schoenbrun Nursing School |
March 1973
| Hadassah Balfour Hospital renamed for former mayor and interior minister Israel Rokach |
| June 1973 | The Friends of Ichilov Hospital Association, the Israeli government, and the Tel Aviv municipality sign an agreement to name the hospital the Sourasky Medical Center |
| October 1973 | The Yom Kippur War begins. Wounded troops are treated at the Medical Center |
| 1978 | Wounded victims of the Coastal Road massacre are taken to the Medical Center for treatment |
| 1980 | The finance minister and the health minister decide to consolidate the three municipal hospitals and name the new institution the Tel Aviv Sourasky Medical Center |
| April 1980 | Dedication of Tel Aviv Sourasky Medical Center The outpatient clinics are transferred from the Hadar Dafna building to the new building. Dedication of the Ida Sourasky Rehabilitation Center building |
| 1986 | Laying of the cornerstone for Dana Hospital; establishment of the Executive Health Program |
| January 1991 | The Medical Center treats 192 people wounded during the Gulf War |
| October 1991 | Dana Children's Hospital dedicated |
| 1992 | The Rokach Hospital is closed, and all of its departments are transferred to the Tel Aviv Medical Center complex on Weizmann Street |
| 1994 | Bombing attacks in Tel Aviv. Approximately 240 people wounded in the bombings of Buses 5 and 20 and at Dizengoff Center are treated at the Medical Center |
| | Trauma Center and National Orthopedic Oncology Department established |
March 1994 December 1994 | Incident involving accidental oxygen pipeline disconnection First kidney transplant takes place |
| January 1995 | Risk Management Department established |
| March 1995 | New emergency room dedicated |
| | Advanced endoscopic surgery unit dedicated |
| November 1995 | Assassination of Prime Minister Yitzhak Rabin. He is treated at the Medical Center after suffering gunshot wounds |
| 1996 | The trauma unit is renamed for Prime Minister Yitzhak Rabin in a ceremony attended by King Hussein of Jordan, Prime Minister Shimon Peres, and Mrs. Leah Rabin |
| July 1997 | Hakirya Hospital is moved, and Lis Maternity Hospital opens |
| September 1997 | Cornerstone for Arison Tower is laid in a ceremony attended by Prime Minister Benjamin Netanyahu and donor Ted Arison |
| February 1998 | Neonatal Department established |
| May 1998 | Construction on hospital tower begins |
| June 1998 | Dedication of Internal Medicine Department H |
| August 1998 | Dedication of gynecology clinics |
| September 1998 | Shustiel Urgent Care Unit and Claridge Israel Emergency Room opened; clinical research center opened |
| October 1998 | Wohl Magnetic Resonance Imaging Center (MRI) opened |
| | Interventional Cardiology Unit opened |
| November 1998 | New post-surgery recovery unit opened |
| April 1999 | Blood bank opens in its new building; intensive surgery department opens at Dana Hospital |
| August 1999 | Pediatric Intensive Care Unit opens in its new building |
| November 1999 | Dedication of the new AIDS center |
| January 2000 | Laboratory center opens |
| February 2000 | Online community health forum, To the Community's Health, opens |
| May 2000 | Chronic Fatigue Syndrome clinic opens |
| June 2000 | Breast imaging center opens |
| July 2000 | Southern and northern parking areas open |
| September 2001 | Surgical Division B is moved to the medical tower |
| November 2001 | The Medical Center's website goes live |
| December 2001 | Intraoperative magnetic resonance imaging (iMRI) introduced; hospital entrance hall and commercial center open |
| January 2002 | Ted Arison Medical Tower inaugurated |
| January 2002 | Surgical Department A and trauma unit are moved to the medical tower |
| February 2002 | Opening of the mobility laboratory at Dana Hospital |
| May 2002 | Orthopedics Department A and B are moved to the tower; PET-CT machine brought into the Isotope Institute |
| December 2002 | Natural Birthing Center opened |
| January 2003 | Neurology, neurosurgery, oncology, and bone-marrow transplant departments moved to the tower |
| April 2003 | Computerized hospital management system goes into continuous operation |
| June 2003 | Information and appointment scheduling center opens |
| November 2003 | Landing pad completed; injured people brought in by air for the first time |
| January 2004 | Linear particle accelerator brought into the Radiation Institute; TARGET financial auditing system for efficient hospital operation inaugurated |
| June 2004 | Picture Archive Communication System (PACS) introduced. PACS enables computerized viewing, saving, and storage of images obtained via MRI, CT, and ultrasound, obviating the need for printing the images. Dedication of new synagogue in memory of the Jews of Krasnik and the surrounding area |
| January 2005 | The Avivim Department for patients requiring nursing care and post-operative recovery is opened |
| June 2005 | The cardiology department is upgraded: the clinics are moved into a new and spacious building, two new stent laboratories are built, and a cardiological day-hospitalization center is opened |
| September 2005 | The Tel Aviv Medical Center wins first place in the Council for a Beautiful Israel's competition for the best-looking hospital |
| September 2005 | The hospital entrance is dedicated; computerized information screens are placed near the operating rooms, enabling real-time tracking of patients' conditions |
| December 2005 | The hospital's main boulevard, named for President Chaim Herzog, is dedicated; the Radiation Institute is reopened after renovation and upgrading |
| February 2006 | The Nephrology Department and Internal Medicine Department 2 are moved to their new locations |
| April 2006 | MommyLis Maternity Club opens; operating rooms are computerized |
| May 2006 | My Net online portal goes live |
| September 2006 | Tel Aviv Medical Center and Micromedic Technologies sign agreement for the first study of its kind for developing a diagnostic product for detecting cancer of the large intestine; public information campaign on washing hands as a disease-prevention method launched |
| | New interventional (angiography) radiology unit opened; dedication of new pulmonary institute, ICU, and pediatric sleep-disturbance center at Dana Hospital |
| January 2007 | Dying Patient Law passed |
| March 2007 | Additional operating room opened at Lis Maternity and Women's Hospital |
| May 2007 | The "Classical Treatment" program, which brings music to hospital patients, is launched in collaboration with Tel Aviv University's Buchmann-Mehta School of Music; the oncology day-treatment unit is moved to its new building on the tenth floor of the tower |
| June 2007 | A computerized hospital management system is introduced into the medical center's laboratories |
| July 2007 | The Urology Department and Ophthalmology Department move to their new quarters on the eleventh floor; the renovated emergency room is opened at Dana Hospital |
| August 2007 | The cornerstone for the Sammy Ofer Heart Center is laid; the Sammy Ofer Science Library is opened on the twelfth floor of the tower |
| February 2008 | The Pseudotumor Cerebri Center opens |
| April 2008 | Establishment of the Center for Complementary Care and Integrative Medicine at the Oncology Institute; MommyLis established as forum with membership |
| May 2008 | Building M is vacated and demolished to prepare for the construction of the Sammy Ofer Heart Center; emergency room opened at Dana-Dwek Hospital |
| June 2009 | Client Relationship Management (CRM) protocol implemented to improve service and patient treatment; Emergency fast-track service launched |
| September 2009 | Tel Aviv Medical Center's beWell program launched to promote preventive medicine and public health |
| October 2009 | Endocrinology Institute moved to its new quarters on the thirteenth floor of the Arison Tower |
| January 2010 | Service-improvement workshops for the medical staff are begun |
| February 2010 | Pediatric intensive care unit wins the Israel Society for Quality award, presented by the President of the State of Israel |
| June 2010 | Orthopedic Division established. Dana Hospital clinics are moved to their new quarters in the Rehabilitation Building. MybeWell service, which provides individual medical information online, is launched |
| November 2010 | Tel Aviv Medical Center wins first prize and the Beautification Flag in the Council for a Beautiful Israel's competition for the best-looking hospital |
| January 2011 | New General Rehabilitation Department opened |
| February 2011 | All surgical departments are brought into the General Surgery Division, directed by Professor Joseph Klausner |
| March 2011 | Sammy Ofer Heart Building and Emergency Underground Hospital dedicated |
| April 2011 | Natural Birthing Center opened at Lis Maternity Hospital |
| May 2011 | The Center for Aesthetic Medicine opened |
| July 2011 | The Pediatric Hemato-oncology and Bone Marrow Transplant Department is moved to its new quarters in Dana-Dwek Children's Hospital |
| January 2012 | The Terem Ichilov emergency clinic opens in Bnei Brak |
| March 2012 | The Center for Women's Health opens at Lis Maternity Hospital |
| June 2012 | A delegation of physicians from the Medical Center, headed by Professor Gabi Barbash, goes to Burgas, Bulgaria, to treat the people wounded in the terror attack. Seven people are treated at the Tel Aviv Medical Center on their arrival in Israel. |
| July 2012 | Officials of the Tel Aviv Medical Center sign a collaboration agreement with officials of the Cincinnati Children's Hospital Medical Center, the third-largest hospital in the United States |
| January 2013 | The American Parkinson's Disease Association recognizes the Center for the Study of Movement, Cognition, and Mobility as an internationally outstanding center in the field of Parkinson's Disease, and awards it a special grant of $60,000 per year for five years to promote high-quality patient care |
| January 2013 | Opening of the Marot Center for the diagnosis and treatment of social and communication disorders and the diagnosis and treatment of children and teenagers on the autistic spectrum in the Institute for Child Development at Dana-Dwek Children's Hospital |
| April 2013 | The "Ichilov" television series premiers on the Yes Docu channel |
| January 2014 | The Tel Aviv Medical Center (Ichilov) receives the Joint Commission International's Gold Seal of Approval for quality and safety |
| February 2014 | Novartis Oncology chooses the Oncology Division's Clinical Research Unit as the first center in Israel to conduct Phase I research for oncology translational medicine, including first-in-human trials |
| January 2015 | Opening of bacteriotherapy service for the treatment of gastrointestinal diseases and hospital-acquired infections |
| May 2015 | New Multidisciplinary Center for Congenital Bone Diseases and Bone Health in Children and Adolescents opens at Dana-Dwek Children's Hospital; construction begins on staff residential tower |
| August 2015 | Professor Ronni Gamzu is appointed director of Tel Aviv Medical Center, replacing Professor Gabi Barbash |
| September 2015 | Professor Gabi Barbash leaves the post of director of the Tel Aviv Medical Center after 22 years of service |
| January 2016 | Department of Voluntary Hospitalization opened in the Medical Center's Psychiatry Division |
| March 2016 | Launch of the Medical Center's vision for "Medical Excellence and Compassionate Care" |
| April 2016 | Top Master's in Healthcare Administration, an American medical site, ranks Dana-Dwek Hospital 19th on their list of the world's most technologically advanced hospitals |
| September 2016 | Cerebrovascular Disease (Stroke) Department established |
| December 2016 | Dana-Dwek Children's Hospital celebrates its 25th anniversary |
January 2017
| The Special Patient Escort Program, which allows a person accompanying the patient to be present when the patient is given information, is launched |
| March 2017 | My Dana: The Family Health Center (which also provides well-baby care as part of the Tipat Halav network) opens on Dizengoff Street |
| June 2017 | The Tel Aviv Medical Center (Ichilov) again receives Joint Commission International's Gold Seal of Approval for quality and safety |
| September 2017 | The Morris Kahn Center for Research in Personalized Medicine is opened on the tenth floor of the Sammy Ofer Heart Building |
| September 2017 | The staff residential tower is dedicated |
| January 2018 | Geriatric Internal Medicine Department A opens |
| February 2018 | Opening of the Sagol Center for Personalized Cancer Therapy and the Nacht Oncology Department and Day Care Unit in the Sammy Ofer Heart Building |
| March 2018 | Gedalya Doron Information and Service Center opens |
| April 2018 | Opening of the renovated Pediatric Intensive-Care Unit in Dana-Dwek Children's Hospital
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October 2018
| Opening of the M.T.S – Medical Technology Simulation Center
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March 2019
| Opening The Department of Thoracic surgery
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March 2020
| Opening Covid-19 departments
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May 2020
| Launching of the 'Ichilov Well' - PCR, Serological Examination
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August 2020
| Opening of the HPB - Hepato-Pancreatico-Biliary center of surgery
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December 2020
| Laying a cornerstone for the new Emergency Medical hospital
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January 2021
| Launching of the Medical innovation and entrepreneurship center - IMED
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June 2022
| Launching of The Sleep Medicine Institute
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October 2021
| Launching of the 'Ichilov Home' services
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January 2022
| Launching of The Institute for Hyperbaric oxygen therapy - hyperbaric chamber
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July 2202
| Launching of The Sylvan Adams Emergency Hospital
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January 2022
| Opening of the 'Lev Fatal - Ichilov' hotel or family members and patients
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September 2023
| Opening of the HOFOM Center children and youth in mental crisis
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October 2023
| Haravot Barzel
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October 2023
| Opening of the protected underground emergency hospital
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October 2023
| Opening of B'shvilam- Hospital Rehabilitation Line Front Ichilov
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