Prof. Nidal Muhanna

01.2006-12.2011    Residency in Otolaryngology, Department of Otolaryngology and Head and Neck Surgery, Shaare Zedek Medical Center

Certifications: MD/PHD

07.2012-07-2016  Clinical/Research Fellowship, Head and Neck Surgical Oncology & Reconstruction.
Department of Otolaryngology - Head and Neck Surgery, University Health Network, University of Toronto, Department of Surgical Oncology, Princess Margaret Cancer Centre. Toronto, Ontario, Canada

Dr. Muhanna completed his ENT surgery training in Jerusalem and he then undertook advanced training in Head and Neck surgery, Skull Base and Reconstructive Surgery in Princes Margaret Cancer center, Toronto, Canada
Dr. Muhanna joined recently the Otolaryngology; Head and Neck and Maxillofacial Surgery division as the Director of the Head and Neck Surgery Unit. Dr Muhanna's areas of expertise include cancers of the oropharynx and larynx, oral cavity, sinonasal cavity, Skull base, cancers of the salivary glands and thyroid surgery, Endoscopic and open surgery , Robotic surgery and reconstructive Micro surgery . 

Dr. Muhanna is leading an Advanced research program within the Department of Otolaryngology/Tel Aviv University. This includes acquiring independent funding from national and international research agencies. The research program will be part of the collaboration with the University of Toronto, TECHNA institution and MARS innovation center, Toronto.
The principles underpinning the research are to integrate modern technology platforms such as molecular imaging, novel nanoparticles and robotics with therapy. This requires development of novel nanoparticles, navigation and tracking techniques that opens the way for precise resection of tumors, while sparing healthy tissues. In this research, we have developed “near real-time” “on the table” three-dimensional images of tumors to provide valuable information as the therapy progresses, leading to more successful interventions and fewer side effects.

The major goals of this research projects revolve around the clinical translation of novel guidance and therapeutic technologies to investigate:
1) Use of novel imaging agents (nanoparticle contrast agents allowing navigation and development of novel applications including tumor and metastatic disease detection.
2) Use of novel therapeutics (nanoparticle for  photothermal and photodynamic  ablation) 
3) Use of novel  photonic imaging  for guidance
4) Potential translational clinical trials for “first in human” use of therapeutic and imaging agents for real time image guided surgery.
5) Use of a novel PET agent for accurate and sensitive detection of tumors and lymph node metastases in head and neck cancer
6) Use of novel technique that provides rapid detection and classification of circulating tumor cell with high sensitivity and selectivity, using immune- magnetic nanoparticles analyzed by a microfluidic device.
7) Elucidating the immunological tumor-host interplay for clinically relevant applications.
8) Development of technologies used for diagnosis of malignancy and for monitoring response to treatment.

2004-2011           Member, Israeli association for the Study of the Liver.
2004-2010           Member, Israeli Association for Gastroenterology & Hepatology.
2005-2011           Member, European association for the study of liver diseases.
2006-2010           Member, American association for the study of liver diseases. 
2009- 2011          Member, The Israeli Society of Otoneurology.
2011-Present       Member, The Israeli Society of Head & Neck Oncology Surgery.
2006-Present      Member, The Israeli Society of Otolaryngology.
2012-Present       Member, American Academy of Otolaryngology—Head and Neck Surgery (AAO-HNS).

• Lip and Oral Cavity Cancer
• Oropharyngeal Cancer
• Hypopharyngeal Cancer
• Laryngeal Cancer
• Thyroid and Parathyroid disorder
• Nasopharyngeal Cancer
• Paranasal Sinus and Nasal Cavity Cancer
• Salivary Gland Cancer
• Unknown Primary SCC
• Head and Neck Sarcoma
• Skin Cancer
• MicroReconstructive Surgery
• Head and Neck Cancer Robotic Surgery
• Sinus and Skull base surgery