Neurology (Pediatrics)

The Leukodystrophy Clinic at Dana-Dwek Children's Hospital, Tel Aviv Medical Center provides a multidisciplinary care for infants, children and adolescents with inherited white matter diseases.

  •  The clinic offers clinical evaluations, diagnostic testing, symptom managements and advanced treatments, genetic consultation as well as support and connection to community services.


  • The multidisciplinary team consists of a pediatric neurologist, physiotherapist, dietitian, speech therapist with expert in swallowing disorders and a social worker. Pediatric geneticist, pediatric orthopedics and other pediatric specialists consult as needed.

  • The team aims to provide best clinical care and to promote research in the field of leukodystrophies in order to improve patient's health, well-being and participation in daily life activities.


Children with various white matter diseases are followed in the clinic.
This includes:

  • PMD- pelizaeus merzbacher disease
  • PMD-LIKE- pelizaeus merzbacher like disease
  • TUBB4A related leukodystrophy (H-ABC etc.)
  • Hikeshi syndrome
  • POLR Related Leukodystrophy
  • Aicardi- Goutie'res syndrome (AGS) 
  • X linked adrenoleukodystrophy (X-ALD)
  • Metachromatic Leukodystrophy (MLD)
  • Canavan Disease
  • Alexander Disease
  • Mucolipidosis type 4 (ML4)
  • Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1)
  • Mitochondrial leukoencephalopathies


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