Hemato-oncology and Bone Marrow Transplantation Department (Pediatrics)

Dana-Dwek Children’s Hospital

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Center of excellence and regional referral center

Dana-Dwek Children’s Hospital Pediatric Hemato-oncology and Bone Marrow Transplantation Department treats infants, children, and youth suffering from acute and chronic blood diseases and from hematological and non-hematological malignant disorders.

 

The department treats approximately 3,500 inpatient and ambulatory patients a year.

Quality multidisciplinary care

The multidisciplinary staff of doctors, nurses, educators, and psycho-sociologists work as a team to provide pediatric patients personalized leading-edge care. Treatment spans the spectrum of settings, including clinic visits, day hospitalization which enables children to return home daily, and hospitalization for extended care.

 

With special focus on the child’s quality of life, the Pediatric Hemato-oncology Department features a child-friendly environment.

Broad range of diseases treated

The department treats the following types of conditions:

 

  1. Anemia of various causes - nutritional deficit, blood cell damage and chronic red blood cell diseases, such as spherocytosis, sickle cell anemia, and thalassemia.
  2. White blood cell conditions, including various neutropenic (low white blood cell count) conditions.
  3. Platelet disorders - the department has a wealth of expertise in immune thrombocytopenic purpura (ITP), the most common platelet disorder in children.
  4. Bone marrow failure syndromes
  5. Diseases of excessive bleeding and thrombophilia - both heredity and congenital.
  6. Histiocytosis - the department has extensive experience in treating Langerhans cell histiocytosis.
  7. Malignant diseases in children:
    • Acute and chronic leukemia
    • Brain tumors -patient care is provided in collaboration with the Department of Pediatric Neurosurgery
    • Bone and soft tissue tumors - patient care provided in collaboration with the Tel Aviv Sourasky Medical Center’s National Oncological Orthopedics Department.
    • Lymph node cancer - lymphoma such as Hodgkin’s lymphoma.
    • Tumors of the kidneys, adrenal glands, testicles and ovaries
    • Rare malignant pediatric tumors

Treatment and tests performed by the department

  • Blood tests – to minimize wait times for blood counts, testing is performed on-site in the department and the results are received within minutes.
  • Hematological investigations and diagnostics including bone marrow testing and spinal taps. These tests are performed pain-free with the help of the Tel Aviv Medical Center’s Dream Service (pediatric service that helps children undergo treatment and testing under sedation).
  • Various blood and blood product transfusions
  • Intravenous iron supplementation
  • Immunotherapy treatments, including immunoglobulins, Rituximab (Mabthera), and anti-D.
  • Chemotherapy administrations – the range of oral, peripheral intravenous, and central venous catheter administrations, performed according to national and international protocols.

Pediatric bone marrow transplantations

The Pediatric Hemato-oncology Department performs a full array of bone marrow transplants (BMT) for children, sourced by self-donated (autologous) marrow and peripheral blood donations and donations from a related or unrelated donor (allogeneic).

Self-donated transplants are performed for malignant conditions, such as recurrent lymphoma, metastasizing bone cancers, high-risk neuroblastoma, and specific types of brain tumors.

Allogeneic BMTs treat malignant diseases, such as hematologic (blood) cancers and non-malignant diseases, such as congenital immunodeficiency states, metabolic disorders, and hereditary blood diseases.

Pre-transplant care
The pediatric BMT service offers pre-transplant care, such as transplant-type decision-making and multidisciplinary testing to prepare the donor and the patient for the procedure.


Transplant accommodations
Transplants are performed in specially designed rooms to accommodate the unique needs of children and to protect the patient from life-threatening infections; rooms feature positive pressure and air filtration systems.

 

Departmental bone marrow transplant services offer essential medical expertise and complementary services to patients with complex health conditions.

 

Post-transplant care
Following the transplant, the patient returns home and remains under close, extended follow-up by the Post-BMT Clinic. During this recovery period, the patient is monitored for successful acceptance of the transplant, tracked for immune system recovery, and treated for potential complications.

The Pediatric Bone Marrow Transplantation Unit is recognized by the European Group for Blood and Marrow Transplantation (EBMT) as an international BMT center for bone marrow transplantation from familial as well as non-familial donors and for autologous transplant.

Complementary services

Patient's family members receive warm assistance in a supportive, comfortable environment by expert clinical, educational, and psychosocial staff.

 

All facilities are designed specifically for children, to make their stay more comfortable, with a play area, cozy seating corners, computers, games, videos, and other kid-friendly entertainment.

 

Many patients are treated at the day hospital facility, which enables them to return home daily in the afternoon. This approach helps preserve the child’s natural surroundings, promoting emotional health.

Contact information

Phone: Day hospitalization: +972-3-697-4270

Phone : Inpatient unit: +972-3-697-4296

Fax: +972-3-697-4931


Location

Dana Children’s Hospital, Floor 1

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Reception Hours

Sun-Thur: 08:00 - 15:00


Appointment